Special additives
DERMAROL® PP
DERMAROL® PP (Vitamin B3) is well known for its performance as anti-aging, skin whitening ingredient able to treat acne, photosensitive dermatitis reducing skin redness while providing moisturisation.It is a building element necessary for cell metabolism to synthetize NAD and NADP, essential coenzymes for cell energy (ATP) production.
Characteristics
| Appearance at 25° C | white crystalline powder |
|---|---|
| Loss on dry % | Max. 0,5 |
| pH (sol. 10% at 25° C) | 5,5 - 7,5 |
| Melting point °C | 128 - 131 |
| UV identification | conform to standard |
| Assay % | 98,5 - 101 |
| IR spectrum | conform to standard |
| Nicotinic acid ppm | Max. 100 |
Applications
DERMAROL PP is very soluble in water (690 g/L at 20,0°C), readily soluble in alcohol, glycerol, ether. Stable to light and heat, it can be processed up to 70°C. Recomended pH of the final formulation: 4,0 - 8,0. DERMAROL PP reduces inflammation (-60%) of Acne (P. Acnes) by the reduction of papules and pustules when used at 4% (In-Vivo study). DERMAROL PP efficacy on skin tone (through inhibition of melanosome transfer) has been demonstrated in a series of clinical studies.At 4% use level, both niacinamide and hydroquinone are as effective. DERMAROL PP supports water barrier function: skin hydration loss (TEWL) was reduced by 27% when skin was treated twice daily with 2% niacinamide for 4 weeks (In-Vivo study) DERMAROL PP shows significant improvement in fine lines and wrinkles following both 8 and 12 weeks of treatment study at 5% (In-Vivo study).
Packaging
DERMAROL PP is delivered in PE drums of 200 kg, and 20 kg or bucket of 15 Kg on shrink wrapped pallets.
The values above were obtained from laboratory and plant trials under CISME’s control. They are, to the best of our knowledge, accurate and reliable, but serve only as a guide and are offered without obligation; they are not a substitute for the prior testing that alone can establish whether a product suits a given use. Users are responsible for compliance with local legislation and for holding the latest version of the data sheet. Data sheet revision 26-03.